pip install -r: OSError: [Errno 13] Permission denied

I am trying to setup Django.

When I run pip install -r requirements.txt, I get the following exception:

    Installing collected packages: amqp, anyjson, arrow, beautifulsoup4, billiard, boto, braintree, celery, cffi, cryptography, Django, django-bower, django-braces, django-celery, django-crispy-forms, django-debug-toolbar, django-disqus, django-embed-video, django-filter, django-merchant, django-pagination, django-payments, django-storages, django-vote, django-wysiwyg-redactor, easy-thumbnails, enum34, gnureadline, idna, ipaddress, ipython, kombu, mock, names, ndg-httpsclient, Pillow, pyasn1, pycparser, pycrypto, PyJWT, pyOpenSSL, python-dateutil, pytz, requests, six, sqlparse, stripe, suds-jurko
    Cleaning up...
    Traceback (most recent call last):
      File "/usr/lib/python2.7/dist-packages/pip/basecommand.py", line 122, in main
        status = self.run(options, args)
      File "/usr/lib/python2.7/dist-packages/pip/commands/install.py", line 283, in run
        requirement_set.install(install_options, global_options, root=options.root_path)
      File "/usr/lib/python2.7/dist-packages/pip/req.py", line 1436, in install
        requirement.install(install_options, global_options, *args, **kwargs)
      File "/usr/lib/python2.7/dist-packages/pip/req.py", line 672, in install
        self.move_wheel_files(self.source_dir, root=root)
      File "/usr/lib/python2.7/dist-packages/pip/req.py", line 902, in move_wheel_files
      File "/usr/lib/python2.7/dist-packages/pip/wheel.py", line 206, in move_wheel_files
        clobber(source, lib_dir, True)
      File "/usr/lib/python2.7/dist-packages/pip/wheel.py", line 193, in clobber
      File "/usr/lib/python2.7/os.py", line 157, in makedirs
        mkdir(name, mode)
    OSError: [Errno 13] Permission denied: '/usr/local/lib/python2.7/dist-packages/amqp-1.4.6.dist-info'

What's wrong and how do I fix this?

Option a) Create a virtualenv, activate it and install:

    virtualenv .venv
    source .venv/bin/activate
    pip install -r requirements.txt

Option b) Install in your homedir:

    pip install --user -r requirements.txt

My recommendation use safe (a) option, so that requirements of this project do not interfere with other projects requirements.

From: stackoverflow.com/q/31512422